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Literature summary extracted from

  • Gilg, A.B.; Tittiger, C.; Blomquist, G.J.
    Unique animal prenyltransferase with monoterpene synthase activity (2009), Naturwissenschaften, 96, 731-735.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.1 expression in Escherichia coli Ips pini
4.2.3.15 expression in Escherichia coli Ips pini

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.15 geranyl diphosphate Ips pini the acyclic monoterpene myrcene is required for the production of the major aggregation pheromone component, ipsdienol myrcene + diphosphate
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Organism

EC Number Organism UniProt Comment Textmining
2.5.1.1 Ips pini Q58GE8 bifunctional enzyme: geranyldiphosphate synthase/myrcene synthase
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4.2.3.15 Ips pini Q58GE8 bifunctional enzyme: geranyldiphosphate synthase/myrcene synthase
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.1 dimethylallyl diphosphate + isopentenyl diphosphate bifunctional enzyme: geranyldiphosphate synthase (EC 2.5.1.1)/myrcene synthase (EC 4.2.3.15). When the recombinant enzyme is incubated with dimethylallyl diphosphate and isopentenyl diphosphate as cosubstrates, the level of geranyl diphosphate formed is approximately tenfold higher than the level of myrcene formed. The data suggest that geranyl diphosphate is a free intermediate in myrcene production Ips pini diphosphate + geranyl diphosphate
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 ?
4.2.3.15 geranyl diphosphate the acyclic monoterpene myrcene is required for the production of the major aggregation pheromone component, ipsdienol Ips pini myrcene + diphosphate
-
 ?
4.2.3.15 geranyl diphosphate bifunctional enzyme: geranyldiphosphate synthase (EC 2.5.1.1)/myrcene synthase (EC 4.2.3.15). When the recombinant enzyme is incubated with dimethylallyl diphosphate and isopentenyl diphosphate as cosubstrates, the level of geranyl diphosphate formed is approximately tenfold higher than the level of myrcene formed. The data suggest that geranyl diphosphate is a free intermediate in myrcene production Ips pini myrcene + diphosphate
-
 ?