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Literature summary extracted from

  • Manceur, A.P.; Driscoll, B.D.; Sun, W.; Audet, J.
    Selective enhancement of the uptake and bioactivity of a TAT-conjugated peptide inhibitor of glycogen synthase kinase-3 (2009), Mol. Ther., 17, 500-507.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.26 (2'Z,3'E)-6-bromoindirubin-3'-oxime
-
 Homo sapiens
2.7.11.26 (2'Z,3'E)-6-bromoindirubin-3'-oxime
-
 Mus musculus
2.7.11.26 lithium
-
 Homo sapiens
2.7.11.26 lithium
-
 Mus musculus
2.7.11.26 trans-activating transcriptor-eIF2B acts as a competitive inhibitor of GSK-3 Homo sapiens
2.7.11.26 trans-activating transcriptor-eIF2B acts as a competitive inhibitor of GSK-3 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.26 Homo sapiens
-
-
-
2.7.11.26 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.26 bone marrow
-
 Mus musculus
-
2.7.11.26 embryonic stem cell
-
 Mus musculus
-
2.7.11.26 primary cell
-
 Mus musculus
-
2.7.11.26 R1 ES cell
-
 Mus musculus
-
2.7.11.26 TF-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.26 ATP + beta-catenin
-
 Mus musculus ADP + phosphorylated beta-catenin
-
 ?
2.7.11.26 ATP + beta-catenin
-
 Homo sapiens ADP + phosphorylated beta-catenin
-
 ?
2.7.11.26 ATP + eIF2B peptide
-
 Mus musculus ADP + phosphorylated eIF2B peptide
-
 ?
2.7.11.26 ATP + eIF2B peptide
-
 Homo sapiens ADP + phosphorylated eIF2B peptide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.26 glycogen synthase kinase-3
-
 Mus musculus
2.7.11.26 glycogen synthase kinase-3
-
 Homo sapiens
2.7.11.26 GSK-3
-
 Mus musculus
2.7.11.26 GSK-3
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.26 ATP
-
 Mus musculus
2.7.11.26 ATP
-
 Homo sapiens