EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.1.129 | expressed in Escherichia coli Rosetta lambdaDE3 cells | Staphylococcus aureus |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.4.1.129 | sitting drop vapor diffusion method, using 100 mM HEPES, pH 7.5, 2 M ammonium sulfate, 20% (v/v) ethylene glycol and 0.28 mM lauryldimethylamine oxide | Staphylococcus aureus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.129 | Moenomycin | - |
Staphylococcus aureus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.129 | Staphylococcus aureus | - |
- |
- |
2.4.1.129 | Staphylococcus aureus NCTC 8325 | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.1.129 | Ni2+-affinity column chromatography, gel filtration, and Mono Q ion-exchange chromatography | Staphylococcus aureus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.129 | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Staphylococcus aureus | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? | |
2.4.1.129 | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Staphylococcus aureus NCTC 8325 | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.129 | PBP2 | - |
Staphylococcus aureus |
2.4.1.129 | penicillin-binding protein 2 | bifunctional peptidoglycan glycosyltransferase/transpeptidase | Staphylococcus aureus |