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Literature summary extracted from
- Multiplicative interaction between the two major mechanisms of permethrin resistance, kdr and cytochrome P450-monooxygenase detoxification, in mosquitoes (2009), J. Evol. Biol., 22, 416-423.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.14.14.1 | medicine | the two major mechanisms that confer resistance to permethrin in Culex mosquitoes are target site insensitivity (i.e. kdr) and enhanced detoxification by cytochrome P450 monooxygenases | Culex quinquefasciatus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.1 | Culex quinquefasciatus | - |
- |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.14.1 | cytochrome P450-monooxygenase | - |
Culex quinquefasciatus |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.14.14.1 | physiological function | for all genotype combinations tested, the mosquitoe exhibits multiplicative interactions between kdr and P450 detoxification, whether the resistance alleles are homozygous or heterozygous | Culex quinquefasciatus |
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