EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.1.1.182 | E43A | mutation located in the S-adenosylmethionine-binding motifs severely reduces methyltransferase activity, the mutation retains the ability to suppress the growth defect of the Era(E200K) strain at a low temperature | Escherichia coli |
2.1.1.182 | E66A | mutation located in the S-adenosylmethionine-binding motifs severely reduces methyltransferase activity, the mutation retains the ability to suppress the growth defect of the Era(E200K) strain at a low temperature | Escherichia coli |
2.1.1.182 | G47A | mutation located in the S-adenosylmethionine-binding motifs severely reduces methyltransferase activity, the mutation retains the ability to suppress the growth defect of the Era(E200K) strain at a low temperature | Escherichia coli |
2.1.1.182 | R248A | mutation at the C-terminal does not affect the methyltransferase activity and fails to suppress the growth defect of the Era(E200K) strain | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.182 | Escherichia coli | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.182 | 4 S-adenosyl-L-methionine + adenine1518/adenine1519 in 16S rRNA | - |
Escherichia coli | 4 S-adenosyl-L-homocysteine + N6-dimethyladenine1518/N6-dimethyladenine1519 in 16S rRNA | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.1.1.182 | KsgA | - |
Escherichia coli |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.1.1.182 | physiological function | KsgA, in addition to its methyltransferase activity, has another unidentified function that plays a role in the suppression of the cold-sensitive phenotype of the Era(E200K) strain. The additional function may be involved in the acid shock response | Escherichia coli |