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Literature summary extracted from
- Oxidative and nitrative modifications of alpha-enolase in cardiac proteins from diabetic rats (2010), Free Radic. Biol. Med., 48, 873-881.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 4.2.1.11 | medicine | the up-regulation of alpha-enolase expression can be a protective mechanism to neutralize oxidative and nitrative stress in diabetes | Rattus norvegicus |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.11 | 47000 | - |
- |
Rattus norvegicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.11 | Rattus norvegicus | P04764 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.1.11 | heart | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.11 | 2-phospho-D-glycerate | - |
Rattus norvegicus | phosphoenolpyruvate + H2O | - |
r |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.2.1.11 | 2-phospho-D-glyceratehydrolyase | - |
Rattus norvegicus |
| 4.2.1.11 | alpha-enolase | - |
Rattus norvegicus |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 4.2.1.11 | Rattus norvegicus | tyrosine nitration inactivates enolase | down |
| 4.2.1.11 | Rattus norvegicus | after 6 weeks of streptozotocin administration, the cardiac proteins from diabetic rats show the levels of alpha-enolase expression and protein tyrosine nitration are clearly increased, whereas the enolase activity and oxidation status are not significantly changed | up |
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Release 2023.1 (January 2023)
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