BRENDA - Enzyme Database

Oxidative and nitrative modifications of alpha-enolase in cardiac proteins from diabetic rats

Lu, N.; Zhang, Y.; Li, H.; Gao, Z.; Free Radic. Biol. Med. 48, 873-881 (2010)

Data extracted from this reference:

Application
EC Number
Application
Commentary
Organism
4.2.1.11
medicine
the up-regulation of alpha-enolase expression can be a protective mechanism to neutralize oxidative and nitrative stress in diabetes
Rattus norvegicus
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.2.1.11
47000
-
-
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.11
Rattus norvegicus
P04764
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.11
heart
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
703811
Rattus norvegicus
phosphoenolpyruvate + H2O
-
-
-
r
Application (protein specific)
EC Number
Application
Commentary
Organism
4.2.1.11
medicine
the up-regulation of alpha-enolase expression can be a protective mechanism to neutralize oxidative and nitrative stress in diabetes
Rattus norvegicus
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.2.1.11
47000
-
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.11
heart
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
703811
Rattus norvegicus
phosphoenolpyruvate + H2O
-
-
-
r
Expression
EC Number
Organism
Commentary
Expression
4.2.1.11
Rattus norvegicus
tyrosine nitration inactivates enolase
down
4.2.1.11
Rattus norvegicus
after 6 weeks of streptozotocin administration, the cardiac proteins from diabetic rats show the levels of alpha-enolase expression and protein tyrosine nitration are clearly increased, whereas the enolase activity and oxidation status are not significantly changed
up
Expression (protein specific)
EC Number
Organism
Commentary
Expression
4.2.1.11
Rattus norvegicus
tyrosine nitration inactivates enolase
down
4.2.1.11
Rattus norvegicus
after 6 weeks of streptozotocin administration, the cardiac proteins from diabetic rats show the levels of alpha-enolase expression and protein tyrosine nitration are clearly increased, whereas the enolase activity and oxidation status are not significantly changed
up