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Literature summary extracted from

  • Brewer, J.M.; McKinnon, J.S.; Phillips, R.S.
    Stopped-flow studies of the reaction of D-tartronate semialdehyde-2-phosphate with human neuronal enolase and yeast enolase 1 (2010), FEBS Lett., 584, 979-983.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.1.11 expressed in Escherichia coli Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.11 Mg2+ Mg2+ is inhibitory at 30 mM to the physiological reaction, but not to the reaction with D-tartronate semialdehyde phosphate Homo sapiens
4.2.1.11 Mg2+ Mg2+ is inhibitory at 30 mM to the physiological reaction, but not to the reaction with D-tartronate semialdehyde phosphate Saccharomyces cerevisiae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.1.11 Mg2+ required for activity Homo sapiens
4.2.1.11 Mg2+ required for activity Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.11 2-phospho-D-glycerate Homo sapiens
-
 phosphoenolpyruvate + H2O
-
 r
4.2.1.11 2-phospho-D-glycerate Saccharomyces cerevisiae
-
 phosphoenolpyruvate + H2O
-
 r

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.11 Homo sapiens
-
-
-
4.2.1.11 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.11
-
 Homo sapiens
4.2.1.11
-
 Saccharomyces cerevisiae

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.11 neuron
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.11 2-phospho-D-glycerate
-
 Homo sapiens phosphoenolpyruvate + H2O
-
 r
4.2.1.11 2-phospho-D-glycerate
-
 Saccharomyces cerevisiae phosphoenolpyruvate + H2O
-
 r
4.2.1.11 D-tartronate semialdehyde phosphate slowly-reacting strongly bound chromophoric substrate Homo sapiens ?
-
 ?
4.2.1.11 D-tartronate semialdehyde phosphate slowly-reacting strongly bound chromophoric substrate Saccharomyces cerevisiae ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.11 2-phospho-D-glycerate hydrolyase
-
 Homo sapiens
4.2.1.11 2-phospho-D-glycerate hydrolyase
-
 Saccharomyces cerevisiae
4.2.1.11 enolase 1
-
 Saccharomyces cerevisiae
4.2.1.11 enolase gamma
-
 Homo sapiens
4.2.1.11 neuronal enolase
-
 Homo sapiens