Literature summary extracted from

Collino, M.; Aragno, M.; Castiglia, S.; Tomasinelli, C.; Thiemermann, C.; Boccuzzi, G.; Fantozzi, R.
Insulin reduces cerebral ischemia/reperfusion injury in the hippocampus of diabetic rats: a role for glycogen synthase kinase-3beta (2009), Diabetes, 58, 235-242.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.11.26	Insulin	insulin induces phosphorylation of the Ser9 residue, thereby inactivating GSK-3beta	Rattus norvegicus
2.7.11.26	TDZD-8	selective GSK-3beta inhibitor, induces phosphorylation of the Ser9 residue, thereby inactivating GSK-3beta	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.11.26	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.11.26	hippocampus	-	Rattus norvegicus	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.11.26	glycogen synthase kinase-3beta	-	Rattus norvegicus
2.7.11.26	GSK-3beta	-	Rattus norvegicus

Expression

EC Number	Organism	Comment	Expression
2.7.11.26	Rattus norvegicus	administration of insulin or TDZD-8 to diabetic rats does not modify the total GSK-3beta mRNA levels	additional information

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Release 2023.1 (January 2023)