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Literature summary extracted from

  • Mueller-Premru, M.; Zidar, N.; Spik, V.C.; Krope, A.; Kikelj, D.
    Benzoxazine series of histidine kinase inhibitors as potential antimicrobial agents with activity against enterococci (2009), Chemotherapy, 55, 414-417.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.13.3 (4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)methanaminium chloride
-
 Enterococcus faecalis
2.7.13.3 (4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)methanaminium chloride
-
 Escherichia coli
2.7.13.3 (4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)methanaminium chloride
-
 Pseudomonas aeruginosa
2.7.13.3 (4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)methanaminium chloride
-
 Staphylococcus aureus
2.7.13.3 2-(4-[2-[4-(4-chlorobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
 Enterococcus faecalis
2.7.13.3 2-(4-[2-[4-(4-chlorobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
 Escherichia coli
2.7.13.3 2-(4-[2-[4-(4-chlorobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
 Pseudomonas aeruginosa
2.7.13.3 2-(4-[2-[4-(4-chlorobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
 Staphylococcus aureus
2.7.13.3 2-(4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
 Enterococcus faecalis
2.7.13.3 2-(4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
 Escherichia coli
2.7.13.3 2-(4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
 Pseudomonas aeruginosa
2.7.13.3 2-(4-[2-[4-(4-cyanobenzyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]ethoxy]phenyl)ethanaminium chloride
-
 Staphylococcus aureus

Organism

EC Number Organism UniProt Comment Textmining
2.7.13.3 Enterococcus faecalis
-
 strains ATCC 29212 and ATCC 51299
-
2.7.13.3 Escherichia coli
-
 strains ATCC 25922 and ATCC 43300
-
2.7.13.3 Pseudomonas aeruginosa
-
 strain ATCC 27853
-
2.7.13.3 Staphylococcus aureus
-
 strain ATCC 29213
-