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Literature summary extracted from

  • Soegaard-Madsen, L.; Johansen, C.; Iversen, L.; Kragballe, K.
    Adalimumab therapy rapidly inhibits p38 mitogen-activated protein kinase activity in lesional psoriatic skin preceding clinical improvement (2010), Br. J. Dermatol., 162, 1216-1223.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.24 additional information activated by phosphorylation Homo sapiens
2.7.11.24 TNF-alpha
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.24 adalimumab
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.24 ATP + a protein Homo sapiens
-
 ADP + a phosphoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.24 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.11.24 phosphoprotein
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.24 NHEK cell
-
 Homo sapiens
-
2.7.11.24 skin lesional psoriatic skin Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.24 ATP + a protein
-
 Homo sapiens ADP + a phosphoprotein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.24 MAP kinase
-
 Homo sapiens
2.7.11.24 MAPK
-
 Homo sapiens
2.7.11.24 mitogen-activated kinase
-
 Homo sapiens
2.7.11.24 p38 mitogen-activated protein kinase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.24 ATP
-
 Homo sapiens