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Literature summary extracted from

  • Binet, R.; Maurelli, A.T.
    The chlamydial functional homolog of KsgA confers kasugamycin sensitivity to Chlamydia trachomatis and impacts bacterial fitness (2009), BMC Microbiol., 9, 279.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.1.1.182 medicine the presence of a functional rRNA dimethylase enzyme belonging to the KsgA family in Chlamydia present an excellent chemotherapeutic target Chlamydia trachomatis

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.182
-
 Chlamydia psittaci
2.1.1.182 expression of the Chlamydia trachomatis L2 KsgA ortholog restored kasugamycin sensitivity to the Escherichia coli ksgA mutant Chlamydia trachomatis

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.182 Chlamydia psittaci C7EP45
-
-
2.1.1.182 Chlamydia psittaci 6BC C7EP45
-
-
2.1.1.182 Chlamydia trachomatis B0B7S3
-
-
2.1.1.182 Chlamydia trachomatis L2 B0B7S3
-
-

Synonyms

EC Number Synonyms Comment Organism
2.1.1.182 KsgA
-
 Chlamydia trachomatis

General Information

EC Number General Information Comment Organism
2.1.1.182 malfunction mutants which contain a frameshift mutation in ksgA are severely impaired for growth Chlamydia trachomatis
2.1.1.182 physiological function KsgA confers kasugamycin sensitivity to Chlamydia trachomatis and impacts bacterial fitness Chlamydia trachomatis