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Literature summary extracted from

  • Theodoratos, A.; Tu, W.J.; Cappello, J.; Blackburn, A.C.; Matthaei, K.; Board, P.G.
    Phenylalanine-induced leucopenia in genetic and dichloroacetic acid generated deficiency of glutathione transferase Zeta (2009), Biochem. Pharmacol., 77, 1358-1363.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.2.1.2 Dichloroacetic acid DCA Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.2.1.2 4-maleylacetoacetate Mus musculus
-
 4-fumarylacetoacetate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.2.1.2 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.2.1.2 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.2.1.2 4-maleylacetoacetate
-
 Mus musculus 4-fumarylacetoacetate
-
 ?
5.2.1.2 chlorofluoroacetic acid + ? activity assay Mus musculus glyoxylate + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.2.1.2 maleylacetoacetate isomerase bifunctional enzyme EC 2.5.1.18, glutathione transferase Zeta, GSTZ1-1 Mus musculus

General Information

EC Number General Information Comment Organism
5.2.1.2 metabolism catalyses a significant step in the catabolism of phenylalanine and tyrosine Mus musculus