EC Number | Application | Comment | Organism |
---|---|---|---|
1.11.1.12 | additional information | an assay for sperm PHGPx activity emerges as a unique tool to evaluate semen quality for sire selection | Bos taurus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.11.1.12 | selenium | - |
Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.12 | glutathione + a lipid hydroperoxide | Bos taurus | - |
glutathione disulfide + lipid + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.11.1.12 | Bos taurus | - |
bull, three Italian beef breeds, Chianina, Marchigiana, Romagnola | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.11.1.12 | spermatozoon | - |
Bos taurus | - |
1.11.1.12 | testis | - |
Bos taurus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.11.1.12 | 0.04 | - |
low-PHGPx group | Bos taurus |
1.11.1.12 | 0.0539 | - |
low-PHGPx, Chianina | Bos taurus |
1.11.1.12 | 0.056 | - |
low-PHGPx, Marchigiana | Bos taurus |
1.11.1.12 | 0.0746 | - |
low-PHGPx, Romagnola | Bos taurus |
1.11.1.12 | 0.13 | - |
high-PHGPx group | Bos taurus |
1.11.1.12 | 0.2242 | - |
high-PHGPx, Chianina | Bos taurus |
1.11.1.12 | 0.2447 | - |
high-PHGPx, Romagnola | Bos taurus |
1.11.1.12 | 0.2453 | - |
high-PHGPx, Marchigiana | Bos taurus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.11.1.12 | glutathione + a lipid hydroperoxide | - |
Bos taurus | glutathione disulfide + lipid + H2O | - |
? | |
1.11.1.12 | glutathione + phosphatidylcholine hydroperoxide | activity assay | Bos taurus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.11.1.12 | GPx4 | - |
Bos taurus |
1.11.1.12 | PHGPX | - |
Bos taurus |
1.11.1.12 | phospholipid hydroperoxide glutathione peroxidase | - |
Bos taurus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.11.1.12 | 23 | - |
activity assay at room temperature | Bos taurus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.11.1.12 | 7.5 | - |
activity assay | Bos taurus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.11.1.12 | glutathione | - |
Bos taurus |
EC Number | Organism | Comment | Expression |
---|---|---|---|
1.11.1.12 | Bos taurus | PHGPx expression is up-regulated in spermatozoa by unknown mechanisms | up |