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Literature summary extracted from

  • Araujo, W.L.; Nunes-Nesi, A.; Trenkamp, S.; Bunik, V.I.; Fernie, A.R.
    Inhibition of 2-oxoglutarate dehydrogenase in potato tuber suggests the enzyme is limiting for respiration and confirms its importance in nitrogen assimilation, (2008), Plant Physiol., 148, 1782-1796.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.105 succinyl phosphonate potent, slow-binding inhibitor of the 2-oxoglutarate dehydrogenase complex, complete inhibition at 0.1 mM Solanum tuberosum
1.2.1.105 succinyl phosphonate carboxy ethyl ester potent, slow-binding inhibitor of the 2-oxoglutarate dehydrogenase complex, complete inhibition at 0.1 mM Solanum tuberosum
1.2.1.105 succinyl phosphonate diethyl ester poor inhibitor of the 2-oxoglutarate dehydrogenase complex Solanum tuberosum
1.2.1.105 succinyl phosphonate phosphono ethyl ester poor inhibitor of the 2-oxoglutarate dehydrogenase complex Solanum tuberosum
1.2.1.105 succinyl phosphonate triethyl ester
-
 Solanum tuberosum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.105 mitochondrion
-
 Solanum tuberosum 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.105 Solanum tuberosum
-
 cultivar Desiree
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.105 tuber
-
 Solanum tuberosum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.105 2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine
-
 Solanum tuberosum [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.105 2-oxoglutarate dehydrogenase complex tricarboxylic acid cycle multienzyme Solanum tuberosum

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.105 NAD+
-
 Solanum tuberosum
1.2.1.105 thiamine diphosphate
-
 Solanum tuberosum