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Literature summary extracted from

  • Zeng, J.; Wu, L.; Zhang, X.; Liu, Y.; Deng, G.; Li, D.
    Oct-2-en-4-ynoyl-CoA as a specific inhibitor of acyl-CoA oxidase (2008), Org. Lett., 10, 4287-4290.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.3.6
-
 Rattus norvegicus
1.3.8.7
-
 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.3.6 oct-2-en-4-ynoyl-CoA irreversible inactivation, pH dependent, higher under basic condition Rattus norvegicus
1.3.8.7 oct-2-yn-4-enoyl-CoA pH-dependent inactivation Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.3.6 peroxisome
-
 Rattus norvegicus 5777
-
1.3.8.7 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.3.6 Rattus norvegicus
-
-
-
1.3.8.7 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.3.6
-
 Rattus norvegicus
1.3.8.7
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.6 acyl-CoA + O2 assay at 25°C Rattus norvegicus trans-2-enoyl-CoA + H2O2
-
 ir

Synonyms

EC Number Synonyms Comment Organism
1.3.3.6 ACO
-
 Rattus norvegicus
1.3.3.6 Acyl-CoA oxidase
-
 Rattus norvegicus
1.3.8.7 ACD
-
 Rattus norvegicus
1.3.8.7 acyl-CoA dehydrogenase
-
 Rattus norvegicus
1.3.8.7 MCAD
-
 Rattus norvegicus
1.3.8.7 medium-chain acyl CoA dehydrogenase
-
 Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.3.3.6 25
-
 assay at Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.3.6 FAD
-
 Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.3.3.6 0.045
-
 oct-2-en-4-ynoyl-CoA
-
 Rattus norvegicus

General Information

EC Number General Information Comment Organism
1.3.3.6 physiological function involved in fatty acid oxidation, essential energy generation Rattus norvegicus
1.3.8.7 physiological function involved in fatty acid oxidation, essential energy generation Rattus norvegicus