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Literature summary extracted from

  • Griswold, A.R.; Nascimento, M.M.; Burne, R.A.
    Distribution, regulation and role of the agmatine deiminase system in mutans streptococci (2009), Oral Microbiol. Immunol., 24, 79-82.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.5.3.12 agmatine
-
 Streptococcus ratti
3.5.3.12 agmatine
-
 Streptococcus mutans
3.5.3.12 agmatine
-
 Streptococcus sobrinus
3.5.3.12 agmatine
-
 Streptococcus criceti
3.5.3.12 agmatine
-
 Streptococcus downei

Application

EC Number Application Comment Organism
3.5.3.12 medicine remove of dental plaque biofilms Streptococcus ratti
3.5.3.12 medicine remove of dental plaque biofilms Streptococcus mutans
3.5.3.12 medicine remove of dental plaque biofilms Streptococcus sobrinus
3.5.3.12 medicine remove of dental plaque biofilms Streptococcus criceti
3.5.3.12 medicine remove of dental plaque biofilms Streptococcus downei

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.3.12 carbohydrate
-
 Streptococcus mutans

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.12 no activity in Streptococcus gordonii
-
-
-
3.5.3.12 no activity in Streptococcus sanguinis
-
 genospecies 1
-
3.5.3.12 Streptococcus criceti
-
-
-
3.5.3.12 Streptococcus criceti AHT
-
-
-
3.5.3.12 Streptococcus downei
-
-
-
3.5.3.12 Streptococcus downei 33748
-
-
-
3.5.3.12 Streptococcus mutans
-
 strain UA159 and strain GS-5
-
3.5.3.12 Streptococcus oralis
-
-
-
3.5.3.12 Streptococcus ratti
-
 strain FA-1 and strain BHT
-
3.5.3.12 Streptococcus salivarius
-
-
-
3.5.3.12 Streptococcus sanguinis
-
 genospecies 2
-
3.5.3.12 Streptococcus sobrinus
-
-
-
3.5.3.12 Streptococcus sobrinus 6715
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.5.3.12 0.0002
-
 strain FA-1, 25 mM glucose, without agmatine Streptococcus ratti
3.5.3.12 0.004
-
 strain FA-1, 25 mM galactose, without agmatine Streptococcus ratti
3.5.3.12 0.006
-
 25 mM glucose + 10 mM agmatine Streptococcus downei
3.5.3.12 0.0097
-
 25 mM sorbitol + 10 mM agmatine Streptococcus sobrinus
3.5.3.12 0.0109
-
 25 mM sorbitol + 10 mM agmatine Streptococcus criceti
3.5.3.12 0.016
-
 25 mM glucose + 10 mM agmatine Streptococcus sobrinus
3.5.3.12 0.02
-
 strain FA-1, 250 mM glucose, without agmatine Streptococcus ratti
3.5.3.12 0.03
-
 strain FA-1, 250 mM glucose + 10 mM agmatine Streptococcus ratti
3.5.3.12 0.032
-
 strain FA-1, 25 mM glucose + 10 mM agmatine Streptococcus ratti
3.5.3.12 0.034
-
 strain FA-1, 25 mM galactose + 10 mM agmatine Streptococcus ratti
3.5.3.12 0.04
-
 strain FA-1, 250 mM galactose, without agmatine Streptococcus ratti
3.5.3.12 0.052
-
 strain BHT, 25 mM glucose + 10 mM agmatine Streptococcus ratti
3.5.3.12 0.058
-
 strain FA-1, 250 mM galactose + 10 mM agmatine Streptococcus ratti
3.5.3.12 0.058
-
 strain UA159, 25 mM glucose + 10 mM agmatine Streptococcus mutans
3.5.3.12 0.078
-
 strain GS-5, 25 mM galactose + 10 mM agmatine Streptococcus mutans
3.5.3.12 0.102
-
 strain FA-1, 25 mM glucose + 10 mM agmatine Streptococcus ratti
3.5.3.12 0.17
-
 strain UA159, 25 mM sorbitol + 10 mM agmatine Streptococcus mutans
3.5.3.12 0.4762
-
 strain UA159, 25 mM galactose + 10 mM agmatine Streptococcus mutans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus sanguinis NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus ratti NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus mutans NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus salivarius NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus oralis NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus sobrinus NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus criceti NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus downei NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus criceti AHT NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus sobrinus 6715 NH3 + N-carbamoylputrescine
-
 ?
3.5.3.12 agmatine + H2O assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid Streptococcus downei 33748 NH3 + N-carbamoylputrescine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.3.12 agmatine deiminase
-
 Streptococcus sanguinis
3.5.3.12 agmatine deiminase
-
 Streptococcus ratti
3.5.3.12 agmatine deiminase
-
 Streptococcus mutans
3.5.3.12 agmatine deiminase
-
 Streptococcus salivarius
3.5.3.12 agmatine deiminase
-
 Streptococcus oralis
3.5.3.12 agmatine deiminase
-
 Streptococcus sobrinus
3.5.3.12 agmatine deiminase
-
 Streptococcus criceti
3.5.3.12 agmatine deiminase
-
 Streptococcus downei

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.3.12 additional information
-
 assay at pH 6.0, 30 min, reaction stopped by 10% trichloroacetic acid Streptococcus sanguinis
3.5.3.12 6
-
 assay at Streptococcus ratti
3.5.3.12 6
-
 assay at Streptococcus mutans
3.5.3.12 6
-
 assay at Streptococcus salivarius
3.5.3.12 6
-
 assay at Streptococcus oralis
3.5.3.12 6
-
 assay at Streptococcus sobrinus
3.5.3.12 6
-
 assay at Streptococcus criceti
3.5.3.12 6
-
 assay at Streptococcus downei