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Literature summary extracted from
- Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs (2009), Mol. Cell. Proteomics, 8, 258-272.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.79 | guanidinium hydrochloride | - |
Homo sapiens |  |
| 3.4.21.79 | guanidinium hydrochloride | - |
Mus musculus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.79 | Homo sapiens | - |
- |
- |
| 3.4.21.79 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.79 | natural killer cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.79 | 28 kDa heat- and acid-stable phosphoprotein + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | 28-kDa heat- and acid-stable phosphoprotein + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | 3110082I17Rik protein + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | 40 S ribosomal protein S25 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | 40 S ribosomal protein S4 + H2O | X isoform | Mus musculus | ? | - |
? | |
| 3.4.21.79 | 40 S ribosomal protein S4 + H2O | X isoform | Homo sapiens | ? | - |
? | |
| 3.4.21.79 | 60 S ribosomal protein L10 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | 60 S ribosomal protein L10 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | 60 S ribosomal protein L3 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | 60 S ribosomal protein L3 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | 60 S ribosomal protein L5 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | 60 S ribosomal protein L5 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | acidic leucine-rich nuclear phosphoprotein 32 family member B + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | acidic leucine-rich nuclear phosphoprotein 32 family member B + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | acidic leucine-rich nuclear phosphoprotein 32 family member E + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | acidic leucine-rich nuclear phosphoprotein 32 family member E + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | actin-like protein 6A + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | actin-like protein 6A + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | anamorsin + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | AQGVISADASNLDDFY + H2O | - |
Homo sapiens | AQGVISAD + ASNLDDFY | - |
? | |
| 3.4.21.79 | AQGVISASASNLDDFY + H2O | - |
Homo sapiens | AQGVISAS + ASNLDDFY | - |
? | |
| 3.4.21.79 | ARF GTPase-activating protein GIT2 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 + H2O | generated with similar efficiency by mouse and human recombinant granzyme B | Homo sapiens | ? | - |
? | |
| 3.4.21.79 | BCL2/adenovirus E1B 19-kDa protein-interacting protein 2 + H2O | generated with similar efficiency by mouse and human recombinant granzyme B | Mus musculus | ? | - |
? | |
| 3.4.21.79 | BID + H2O | efficient cleavage of mouse and human Bid by human granzyme B | Homo sapiens | truncated BID + ? | - |
? | |
| 3.4.21.79 | cell division cycle 5-like protein + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | cell division cycle 5-like protein + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | cell division cycle 5-related protein + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | cell division cycle 5-related protein + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | chromodomain-helicase-DNA-binding protein 7 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | chromodomain-helicase-DNA-binding protein 7 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | dedicator of cytokinesis protein 2 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | double strand break repair protein MRE11A + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | E3 SUMO-protein ligase RanBP2 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | E3 SUMO-protein ligase RanBP2 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | embryo heart cDNA + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | enhancer of mRNA-decapping protein 3 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | enhancer of mRNA-decapping protein 3 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | eukaryotic translation initiation factor 2 subunit 2 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | exportin-5 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | gamma-taxilin + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | gamma-taxilin + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | GTP-binding protein 1 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | kinesin family member 21A + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | kinesin family member 21A + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | LEADKGKLEYD + H2O | is a far better substrate for mouse granzyme B as compared with human granzyme B | Mus musculus | LEAD + KGKLEYD | - |
? | |
| 3.4.21.79 | LEADKGKLEYD + H2O | is a far better substrate for mouse granzyme B as compared with human granzyme B | Homo sapiens | LEAD + KGKLEYD | - |
? | |
| 3.4.21.79 | MFLJ00057 protein + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | microtubule-associated protein 4 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | microtubule-associated protein 4 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | additional information | mediates cleavage at Asn36 (neo-N terminus: LALLEEIEAENR) in the mouse and at Asp37 (neo-N terminus: LALMEEMEAEHR) in the human DNA polymerase delta catalytic subunit | Homo sapiens | ? | - |
? | |
| 3.4.21.79 | additional information | no efficient cleavage of mouse and human Bid by mouse granzyme B | Mus musculus | ? | - |
? | |
| 3.4.21.79 | negative elongation factor E + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | nipped-B-like protein + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | nipped-B-like protein + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | nuclease-sensitive element-binding protein 1 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | nucleolin + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | nucleolin + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | nucleosome assembly protein 1-like + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | pallidin + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | pallidin + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | peptidyl-prolyl cis-trans isomerase G + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | peptidyl-prolyl cis-trans isomerase G + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | peptidyl-prolyl cis-trans isomerase-like 4 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | pericentriolar material 1 protein + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | polypyrimidine tract-binding protein + H2O | 2times more efficiently cleaved by mouse versus human recombinant granzyme B | Mus musculus | ? | - |
? | |
| 3.4.21.79 | polypyrimidine tract-binding protein + H2O | 2times more efficiently cleaved by mouse versus human recombinant granzyme B | Homo sapiens | ? | - |
? | |
| 3.4.21.79 | probable rRNA-processing protein EBP2 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | protein phosphatase 1G + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | RNA-binding protein 28 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | RNA-binding protein 28 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | scaffold attachment factor B + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | serine/arginine-repetitive matrix protein 1 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | serine/arginine-repetitive matrix protein 2 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | serine/arginine-repetitive matrix protein 2 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | serine/threonine protein kinase N1 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | serine/threonine protein kinase N1 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | serum deprivation-response protein + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | splicing factor 3B subunit 1 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | splicing factor 3B subunit 1 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | squamous cell carcinoma antigen recognized by T-cells 3 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | squamous cell carcinoma antigen recognized by T-cells 3 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | T-complex protein 1 subunit alpha + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | T-complex protein 1 subunit alpha + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | testis-specific Y-encoded-like protein 2 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | transcription elongation factor A protein 1 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | U3 small nucleolar RNA-associated protein 18 homolog + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | U4/U6.U5 tri-snRNP-associated protein 1 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | ubiquitin C-terminal hydrolase 10 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | ubiquitin thioesterase OTUB1 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.79 | ubiquitin thioesterase OTUB1 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.79 | uncharacterized protein KIAA0859 + H2O | - |
Mus musculus | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.79 | GrB | - |
Mus musculus |
| 3.4.21.79 | GrB | - |
Homo sapiens |
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