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Literature summary extracted from

  • He, T.; Joyner, M.J.; Katusic, Z.S.
    Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells (2009), Microvasc. Res., 78, 447-452.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.11.1.9 additional information aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells, increasing selenium concentration in the cell culture does not affect the protein levels of GPX1, suggesting the reduced GPX1 in old subject's endothelial progenitor cells is selenium independent Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.11.1.9 selenium the enzyme contains selenium Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.9 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.1.9 endothelial progenitor cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.9 glutathione + ROOH
-
 Homo sapiens glutathione disulfide + ROH + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.11.1.9 glutathione peroxidase-1
-
 Homo sapiens
1.11.1.9 GPX1
-
 Homo sapiens