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Literature summary extracted from

  • Miyoshi, Y.; Hamase, K.; Tojo, Y.; Mita, M.; Konno, R.; Zaitsu, K.
    Determination of D-serine and D-alanine in the tissues and physiological fluids of mice with various D-amino-acid oxidase activities using two-dimensional high-performance liquid chromatography with fluorescence detection (2009), J. Chromatogr. B, 877, 2506-2512.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.4.3.3 additional information comparison of D-Ser and D-Ala contents in different tissues in wild-type DAO+/+ mice with knockout mice DAO-/- and heterozygous DAO+/- mice, detailed overview Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.3 Mus musculus P18894
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.3 cerebellum
-
 Mus musculus
-
1.4.3.3 cerebral cortex
-
 Mus musculus
-
1.4.3.3 hippocampus
-
 Mus musculus
-
1.4.3.3 hypothalamus
-
 Mus musculus
-
1.4.3.3 kidney
-
 Mus musculus
-
1.4.3.3 liver
-
 Mus musculus
-
1.4.3.3 medulla oblongata
-
 Mus musculus
-
1.4.3.3 olfactory bulb
-
 Mus musculus
-
1.4.3.3 pancreas
-
 Mus musculus
-
1.4.3.3 pituitary gland
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.3.3 additional information
-
 comparison of D-Ser and D-Ala contents in different tissues in wild-type DAO+/+ mice with knockout mice DAO-/- and heterozygous DAO+/- mice, detailed overview Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.3 D-alanine + H2O + O2 the D-amino acid is a modulator of the N-methyl-D-aspartate receptor mediated neurotransmission Mus musculus pyruvate + NH3 + H2O2
-
 ?
1.4.3.3 D-serine + H2O + O2 the D-amino acid is a modulator of the N-methyl-D-aspartate receptor mediated neurotransmission Mus musculus 2-oxo-3-hydroxypropionate + NH3 + H2O2
-
 ?