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Literature summary extracted from

  • Ogut, O.; Brozovich, F.V.
    The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failure (2008), J. Cell. Mol. Med., 12, 2158-2164.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.53 type I cGMP-dependent protein kinase
-
 Homo sapiens

Application

EC Number Application Comment Organism
3.1.3.53 medicine congestive heart failure is associated with a decrease in the COOH-terminus leucine zipper and the myosin targeting subunit of MLPC expression Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.53 20000
-
 1 * 20000 + 1 * 38000 + 1 * 110000 Homo sapiens
3.1.3.53 38000
-
 1 * 20000 + 1 * 38000 + 1 * 110000 Homo sapiens
3.1.3.53 110000
-
 1 * 20000 + 1 * 38000 + 1 * 110000 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.53 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.53 smooth muscle
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.53 myosin light-chain phosphate + H2O 20 kDa myosin light chain Homo sapiens myosin light-chain + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.53 trimer 1 * 20000 + 1 * 38000 + 1 * 110000 Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.1.3.53 mLC phosphatase
-
 Homo sapiens
3.1.3.53 MLCP
-
 Homo sapiens
3.1.3.53 myosin light chain phosphatase
-
 Homo sapiens