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Literature summary extracted from

  • Chowanadisai, W.; Bauerly, K.A.; Tchaparian, E.; Wong, A.; Cortopassi, G.A.; Rucker, R.B.
    Pyrroloquinoline quinone stimulates mitochondrial biogenesis through CREB phosphorylation and increased PGC-1{alpha} expression (2010), J. Biol. Chem., 285, 142-152.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.1.1.9 pyrroloquinoline quinone PQQ Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.9 mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.1.1.9 ferrocytochrome c + O2 + H+ Mus musculus
-
 ferricytochrome c + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.9 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.1.1.9 HEPA 1-6 cell
-
 Mus musculus
-
7.1.1.9 hepatocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.9 ferrocytochrome c + O2 + H+
-
 Mus musculus ferricytochrome c + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.1.1.9 cytochrome c oxidase
-
 Mus musculus

Expression

EC Number Organism Comment Expression
7.1.1.9 Mus musculus exposure of mouse Hepa1-6 cells to 10-30 microM pyrroloquinoline quinone for 24-48 h results in increased cytochrome c oxidase activity up