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Literature summary extracted from

  • Gillette, T.G.; Kumar, B.; Thompson, D.; Slaughter, C.A.; DeMartino, G.N.
    Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasome (2008), J. Biol. Chem., 283, 31813-31822.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.6.1.5 additional information carboxypeptidase treatment of PA700 inhibits its binding to and activation of the proteasome Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.5 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.5 erythrocyte
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide
-
 Bos taurus ADP + phosphate + unfolded polypeptide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.5 19S regulatory particle
-
 Bos taurus
5.6.1.5 ATPase regulatory complex PA700
-
 Bos taurus