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Literature summary extracted from

  • Szajda, S.D.; Snarska, J.; Jankowska, A.; Puchalski, Z.; Zwierz, K.
    Isoenzymes A and B of N-acetyl-beta-D-hexosaminidase in serum and urine of patients with pancreatic cancer (2008), Hepatogastroenterology, 55, 695-698.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.2.1.52 additional information concentration and specific activity of total HEX and isoenzyme A are significantly higher in the serum and urine of pancreatic cancer patients in comparison with the concentration and specific activity in the serum and urine of healthy people. Specific activity of isoenzyme B in serum and urine has a tendency to increase in comparison to the control Homo sapiens

Application

EC Number Application Comment Organism
3.2.1.52 medicine activity of HEX and its isoenzyme A determined in the serum and urine can be used as a potential marker of pancreatic adenocarcinoma Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.52 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.52 serum
-
 Homo sapiens
-
3.2.1.52 urine
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.52 4-nitrophenyl beta-N-acetyl-D-glucosaminide + H2O
-
 Homo sapiens 4-nitrophenol + N-acetyl-beta-D-glucosamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.52 Hex A
-
 Homo sapiens
3.2.1.52 Hex B
-
 Homo sapiens
3.2.1.52 N-acetyl-beta-D-hexosaminidase
-
 Homo sapiens