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Literature summary extracted from

  • Eriksson, S.E.; Prast-Nielsen, S.; Flaberg, E.; Szekely, L.; Arner, E.S.
    High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy (2009), Free Radic. Biol. Med., 47, 1661-1671.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.1.9 1-chloro-2,4-dinitrobenzene
-
 Homo sapiens
1.8.1.9 1-chloro-2,4-dinitrobenzene
-
 Rattus norvegicus
1.8.1.9 auranofin
-
 Homo sapiens
1.8.1.9 auranofin
-
 Rattus norvegicus
1.8.1.9 cisplatin
-
 Homo sapiens
1.8.1.9 cisplatin
-
 Rattus norvegicus
1.8.1.9 juglone
-
 Homo sapiens
1.8.1.9 juglone
-
 Rattus norvegicus
1.8.1.9 menadione
-
 Homo sapiens
1.8.1.9 menadione
-
 Rattus norvegicus
1.8.1.9 oxaliplatin
-
 Homo sapiens
1.8.1.9 oxaliplatin
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.8.1.9 55000
-
 SDS-PAGE Homo sapiens
1.8.1.9 55000
-
 SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.9 Homo sapiens Q16881
-
-
1.8.1.9 Rattus norvegicus O89049
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.1.9 A-549 cell
-
 Homo sapiens
-

Subunits

EC Number Subunits Comment Organism
1.8.1.9 ? x * 55000, SDS-PAGE Homo sapiens
1.8.1.9 ? x * 55000, SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
1.8.1.9 thioredoxin reductase 1
-
 Homo sapiens
1.8.1.9 thioredoxin reductase 1
-
 Rattus norvegicus
1.8.1.9 TrxR1
-
 Homo sapiens
1.8.1.9 TrxR1
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.9 NADPH
-
 Homo sapiens
1.8.1.9 NADPH
-
 Rattus norvegicus