Literature summary extracted from

Diz, D.I.; Garcia-Espinosa, M.A.; Gegick, S.; Tommasi, E.N.; Ferrario, C.M.; Ann Tallant, E.; Chappell, M.C.; Gallagher, P.E.
Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats (2008), Exp. Physiol., 93, 694-700.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.15.1	lisinopril	-	Rattus norvegicus
3.4.15.1	additional information	not inhibited by MLN4760, SCH39370, amastatin bestatin, chymostatin, and p-chloromercuribenzoate	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.4.15.1	membrane	-	Rattus norvegicus	16020	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.4.15.1	angiotensin I + H2O	Rattus norvegicus	-	angiotensin II + L-His-L-Leu	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.15.1	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.15.1	blood plasma	-	Rattus norvegicus	-
3.4.15.1	medulla oblongata	dorsomedial medulla	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.15.1	angiotensin I + H2O	-	Rattus norvegicus	angiotensin II + L-His-L-Leu	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.15.1	ACE	-	Rattus norvegicus
3.4.15.1	angiotensin-converting enzyme	-	Rattus norvegicus

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Release 2023.1 (January 2023)