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Literature summary extracted from

  • Li, H.Q.; Xiao, Z.P.; Yin-Luo, Z.P.; Yan, T.; Lv, P.C.; Zhu, H.L.
    Amines and oximes derived from deoxybenzoins as Helicobacter pylori urease inhibitors (2009), Eur. J. Med. Chem., 44, 2246-2251.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.5 1-(2,4-dihydroxyphenyl)-2-(4-fluorophenyl)ethanone oxime
-
 Helicobacter pylori
3.5.1.5 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone oxime
-
 Helicobacter pylori
3.5.1.5 1-(2-hydroxy-4,6-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanone oxime
-
 Helicobacter pylori
3.5.1.5 1-(3,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethanone oxime
-
 Helicobacter pylori
3.5.1.5 2-(1-amino-2-(4-hydroxyphenyl)ethyl)-4-methoxybenzene-1,3,5-triol
-
 Helicobacter pylori
3.5.1.5 2-(1-amino-2-(4-hydroxyphenyl)ethyl)benzene-1,3,5-triol
-
 Helicobacter pylori
3.5.1.5 2-(4-fluorophenyl)-1-(2,3,4-trihydroxyphenyl)ethanone oxime
-
 Helicobacter pylori
3.5.1.5 2-(4-hydroxyphenyl)-1-(2,3,4-trihydroxyphenyl)ethanone oxime
-
 Helicobacter pylori
3.5.1.5 2-(4-hydroxyphenyl)-1-(2,4,6-trihydroxy-3-methoxyphenyl)ethanone oxime
-
 Helicobacter pylori
3.5.1.5 2-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone oxime
-
 Helicobacter pylori
3.5.1.5 2-(4-methoxyphenyl)-1-(2,3,4-trimethoxyphenyl)ethanamine
-
 Helicobacter pylori
3.5.1.5 4-(1-amino-2-(4-fluorophenyl)ethyl)benzene-1,2,3-triol
-
 Helicobacter pylori
3.5.1.5 4-(1-amino-2-(4-fluorophenyl)ethyl)benzene-1,3-diol
-
 Helicobacter pylori
3.5.1.5 4-(1-amino-2-(4-hydroxyphenyl)ethyl)benzene-1,2,3-triol
-
 Helicobacter pylori
3.5.1.5 4-(1-amino-2-(4-hydroxyphenyl)ethyl)benzene-1,2-diol
-
 Helicobacter pylori
3.5.1.5 4-(1-amino-2-(4-methoxyphenyl)ethyl)benzene-1,3-diol
-
 Helicobacter pylori
3.5.1.5 Acetohydroxamic acid
-
 Helicobacter pylori

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.5 Helicobacter pylori
-
 ATCC 43504
-

Synonyms

EC Number Synonyms Comment Organism
3.5.1.5 Urea amidohydrolase
-
 Helicobacter pylori
3.5.1.5 urease
-
 Helicobacter pylori

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.5.1.5 0.011
-
-
 Helicobacter pylori 4-(1-amino-2-(4-hydroxyphenyl)ethyl)benzene-1,2,3-triol
3.5.1.5 0.017
-
-
 Helicobacter pylori Acetohydroxamic acid
3.5.1.5 0.047
-
-
 Helicobacter pylori 4-(1-amino-2-(4-hydroxyphenyl)ethyl)benzene-1,2-diol