Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Morisseau, C.; Newman, J.W.; Wheelock, C.E.; Hill Iii, T.; Morin, D.; Buckpitt, A.R.; Hammock, B.D.
    Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase (2008), Chem. Res. Toxicol., 21, 951-957.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.3.2.9 expressed in a baculovirus expression system in High Five insect cell cultures (derived from Trichoplusia ni) Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.9 2-nonylsulfanyl-propionamide
-
 Rattus norvegicus
3.3.2.9 elaidamide
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.9 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.9 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.3.2.9 Q-Sepharose column chromatography Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.9 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.9 cis-stilbene oxide + H2O
-
 Rattus norvegicus (1R,2R)-1,2-diphenylethane-1,2-diol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.3.2.9 mEH
-
 Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.3.2.9 0.000072
-
 2-nonylsulfanyl-propionamide in Tris/HCl buffer (0.1 M, pH 9.0), at 30°C Rattus norvegicus