Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Morikawa, T.; Funakoshi, K.; Ninomiya, K.; Yasuda, D.; Miyagawa, K.; Matsuda, H.; Yoshikawa, M.
    Medicinal foodstuffs. XXXIV. Structures of new prenylchalcones and prenylflavanones with TNF-alpha and aminopeptidase N inhibitory activities from Boesenbergia rotunda (2008), Chem. Pharm. Bull., 56, 956-962.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 (+)-4-hydroxypanduratin A 54.8% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (+)-isopanduratin A 29.3% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (+)-krachaizin A 27.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (+)-krachaizin B 76.2% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (+)-panduratin A 61.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (-)-4-hydroxypanduratin A 39.6% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (-)-isopanduratin A 95.3% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (-)-krachaizin A 21.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (-)-krachaizin B 51.0% inhibition at 0.03 mM Homo sapiens
3.4.11.2 (-)-panduratin A 95.2% inhibition at 0.03 mM Homo sapiens
3.4.11.2 2,4-dihydroxy-6-phenethylbenzoic acid methyl ester 22.8% inhibition at 0.03 mM Homo sapiens
3.4.11.2 2,6-dihydroxy-4-methoxydihydrochalcone 14.8% inhibition at 0.03 mM Homo sapiens
3.4.11.2 5,6-dehydrokawain 17.7% inhibition at 0.03 mM Homo sapiens
3.4.11.2 5,7-dihydroxy-8-geranylflavanone 28.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 7,4'-dihydroxy-5-methoxyflavanone 14.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 7-methoxy-5-hydroxy-8-geranylflavanone 17.0% inhibition at 0.03 mM Homo sapiens
3.4.11.2 alpinetin 36.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 cardamonin 37.2% inhibition at 0.03 mM Homo sapiens
3.4.11.2 curcumin 31.9% inhibition at 0.03 mM Homo sapiens
3.4.11.2 geraniol 7.6% inhibition at 0.03 mM Homo sapiens
3.4.11.2 geranyl-2,4-dihydroxy-6-phenylbenzoate 89.4% inhibition at 0.03 mM Homo sapiens
3.4.11.2 pinocembrin 13.3% inhibition at 0.03 mM Homo sapiens
3.4.11.2 pinostrobin 10.5% inhibition at 0.03 mM Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 L-Ala-p-nitroanilide + H2O
-
 Homo sapiens L-Ala + p-nitroaniline
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.2 aminopeptidase N
-
 Homo sapiens
3.4.11.2 APN
-
 Homo sapiens