EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.18.1 | (2E)-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-(3,4-dihydroxyphenyl)-N-(4-hydroxybenzyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dihydroxyphenyl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-(4-chlorophenyl)-N-[2-(4-chlorophenyl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-(4-hydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide | strong tyrosinase inhibitory potential | Agaricus bisporus | |
1.14.18.1 | (2E)-3-(4-methoxyphenyl)-N-(1-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-(4-methoxyphenyl)-N-(2-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-phenyl-N-(1-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-3-phenyl-N-(2-phenylethyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-N-(3,4-dihydroxybenzyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-N-(4-chlorobenzyl)-3-phenylprop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-N-benzyl-3-(3,4-dihydroxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-N-benzyl-3-(4-hydroxyphenyl)prop-2-enamide | strong tyrosinase inhibitory potential | Agaricus bisporus | |
1.14.18.1 | (2E)-N-benzyl-3-(4-methoxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-N-benzyl-3-phenylprop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-N-[2-(4-chlorophenyl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | (2E)-N-[2-(4-chlorophenyl)ethyl]-3-phenylprop-2-enamide | - |
Agaricus bisporus | |
1.14.18.1 | 3-hydroxycinnamic acid | - |
Agaricus bisporus | |
1.14.18.1 | caffeic acid | i.e. 3,4-dihydroxycinnamic acid | Agaricus bisporus | |
1.14.18.1 | Cinnamic acid | - |
Agaricus bisporus | |
1.14.18.1 | hydroquinone | - |
Agaricus bisporus | |
1.14.18.1 | kojic acid | - |
Agaricus bisporus | |
1.14.18.1 | p-coumaric acid | - |
Agaricus bisporus | |
1.14.18.1 | phenylethylamide | - |
Agaricus bisporus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.18.1 | Agaricus bisporus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.18.1 | L-tyrosine + O2 | - |
Agaricus bisporus | dopaquinone + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.18.1 | tyrosinase | - |
Agaricus bisporus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.14.18.1 | 0.028 | - |
- |
Agaricus bisporus | (2E)-N-benzyl-3-(4-hydroxyphenyl)prop-2-enamide | |
1.14.18.1 | 0.03 | - |
- |
Agaricus bisporus | (2E)-3-(4-hydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide | |
1.14.18.1 | 0.037 | - |
- |
Agaricus bisporus | hydroquinone | |
1.14.18.1 | 0.075 | - |
- |
Agaricus bisporus | kojic acid | |
1.14.18.1 | 0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-3-phenyl-N-(2-phenylethyl)prop-2-enamide | |
1.14.18.1 | 0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-N-[2-(4-chlorophenyl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide | |
1.14.18.1 | 0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-N-benzyl-3-phenylprop-2-enamide | |
1.14.18.1 | 0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-N-(4-chlorobenzyl)-3-phenylprop-2-enamide | |
1.14.18.1 | 0.1 | - |
IC50 above 0.1 mM | Agaricus bisporus | (2E)-3-phenyl-N-(1-phenylethyl)prop-2-enamide | |
1.14.18.1 | 0.2 | - |
- |
Agaricus bisporus | p-coumaric acid | |
1.14.18.1 | 0.25 | - |
- |
Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide | |
1.14.18.1 | 0.25 | - |
- |
Agaricus bisporus | (2E)-N-benzyl-3-(3,4-dihydroxyphenyl)prop-2-enamide | |
1.14.18.1 | 0.35 | - |
- |
Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-(4-hydroxybenzyl)prop-2-enamide | |
1.14.18.1 | 0.35 | - |
- |
Agaricus bisporus | (2E)-N-(3,4-dihydroxybenzyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide | |
1.14.18.1 | 0.4 | - |
- |
Agaricus bisporus | caffeic acid | |
1.14.18.1 | 0.6 | - |
- |
Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]prop-2-enamide | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | Cinnamic acid | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | 3-hydroxycinnamic acid | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(3,4-dihydroxyphenyl)ethyl]prop-2-enamide | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-(2-phenylethyl)prop-2-enamide | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(4-methoxyphenyl)-N-(2-phenylethyl)prop-2-enamide | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-N-[2-(4-chlorophenyl)ethyl]-3-phenylprop-2-enamide | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(4-chlorophenyl)-N-[2-(4-chlorophenyl)ethyl]prop-2-enamide | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-N-benzyl-3-(4-methoxyphenyl)prop-2-enamide | |
1.14.18.1 | 1 | - |
IC50 above 1 mM | Agaricus bisporus | (2E)-3-(4-methoxyphenyl)-N-(1-phenylethyl)prop-2-enamide |