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Literature summary extracted from

  • Brzezinski, M.R.; Abraham, T.L.; Stone, C.L.; Dean. R.A.; Bosron, W.F.
    Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production of benzoylecgonine and the formation of cocaethylene from alcohol and cocaine (1994), Biochem. Pharmacol., 48, 1747-1755.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.1 59000
-
 3 * 59000, SDS-PAGE Homo sapiens
3.1.1.1 170000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.1 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.1.1 glycoprotein
-
 Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.1
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.1 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.1 4-methylumbelliferyl acetate + H2O
-
 Homo sapiens 4-methylumbelliferone + acetate
-
 ?
3.1.1.1 cocaine + H2O
-
 Homo sapiens O-benzoylecgonine + methanol
-
 ?
3.1.1.1 additional information the enzyme also catalyzes the ethyl transesterification of cocaine with ethanol to form cocaethylene Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.1 trimer 3 * 59000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.1.1.1 cocaine:benzoylecgonine esterase
-
 Homo sapiens

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.1.1.1 Homo sapiens isoelectric focusing
-
 5.8