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Literature summary extracted from

  • Rothery, R.A.; Chatterjee, I.; Kiema, G.; McDermott, M.T.; Weiner, J.H.
    Hydroxylated naphthoquinones as substrates for Escherichia coli anaerobic reductases (1998), Biochem. J., 332, 35-41.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.5.1 2-n-heptyl-4-hydroxyquinoline N-oxide
-
 Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.7.5.1 0.057
-
 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinol pH 7 Escherichia coli
1.7.5.1 0.282
-
 5-hydroxy-2-methyl-1,4-naphthoquinol pH 7 Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.7.5.1 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.5.1 nitrate + 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinol
-
 Escherichia coli nitrite + 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone + H2O
-
 ?
1.7.5.1 nitrate + 5-hydroxy-2-methyl-1,4-naphthoquinol
-
 Escherichia coli nitrite + 5-hydroxy-2-methyl-1,4-naphthoquinone + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.7.5.1 NarGHI
-
 Escherichia coli

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.7.5.1 68
-
 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinol pH 7 Escherichia coli
1.7.5.1 120
-
 5-hydroxy-2-methyl-1,4-naphthoquinol pH 7 Escherichia coli

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.7.5.1 0.00008
-
 pH 7, substrate: 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinol Escherichia coli 2-n-heptyl-4-hydroxyquinoline N-oxide