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Literature summary extracted from

  • Xu, T.T.; Bai, Z.Z.; Wang, L.J.; He, B.F.
    Breeding of D(-)-lactic acid high producing strain by low-energy ion implantation and preliminary analysis of related metabolism (2008), Appl. Biochem. Biotechnol., 160, 314-321.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.28 additional information random mutagensis, and screening for gain-of-function mutants, mutant Y2-8 shows improved D(-)-lactate synthesis, which is 2fold increased compared to the wild-type strain DX12 Sporolactobacillus sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.28 pyruvate + NADH Sporolactobacillus sp.
-
 (R)-lactate + NAD+
-
 r
1.1.1.28 pyruvate + NADH Sporolactobacillus sp. DX12
-
 (R)-lactate + NAD+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.28 Sporolactobacillus sp.
-
 isolated from soil
-
1.1.1.28 Sporolactobacillus sp. DX12
-
 isolated from soil
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.28 pyruvate + NADH
-
 Sporolactobacillus sp. (R)-lactate + NAD+
-
 r
1.1.1.28 pyruvate + NADH
-
 Sporolactobacillus sp. DX12 (R)-lactate + NAD+
-
 r
1.1.1.28 pyruvate + NADH + H+
-
 Sporolactobacillus sp. (R)-lactate + NAD+
-
 r
1.1.1.28 pyruvate + NADH + H+
-
 Sporolactobacillus sp. DX12 (R)-lactate + NAD+
-
 r