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Literature summary extracted from

  • Jang, B.; Kim, E.; Choi, J.K.; Jin, J.K.; Kim, J.I.; Ishigami, A.; Maruyama, N.; Carp, R.I.; Kim, Y.S.; Choi, E.K.
    Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis (2008), Am. J. Pathol., 173, 1129-1142.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.15 Mus musculus Q08642
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.3.15 astrocyte PAD2 immunoreactivity is increased in Scrapie-infected brains, with staining detected primarily in reactive astrocytes Mus musculus
-
3.5.3.15 brain expression levels of PAD2 protein as well as its enzyme activity are significantly increased in brain sections of Scrapie-infected mice, including hippocampus, brain stem, and striatum Mus musculus
-
3.5.3.15 brain stem
-
 Mus musculus
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3.5.3.15 cerebellum
-
 Mus musculus
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3.5.3.15 cerebral cortex
-
 Mus musculus
-
3.5.3.15 corpus striatum
-
 Mus musculus
-
3.5.3.15 hippocampus
-
 Mus musculus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.3.15 aldolase 1A L-Arg + H2O
-
 Mus musculus aldolase 1A L-citrulline + NH3
-
 ?
3.5.3.15 aldolase 3C L-Arg + H2O
-
 Mus musculus aldolase 3C L-citrulline + NH3
-
 ?
3.5.3.15 aldolase C L-Arg + H2O
-
 Mus musculus aldolase C L-citrulline + NH3
-
 ?
3.5.3.15 alpha-enolase 1 L-Arg + H2O
-
 Mus musculus alpha-enolase 1 L-citrulline + NH3
-
 ?
3.5.3.15 benzoyl-L-arginine ethyl ester + H2O
-
 Mus musculus benzoyl-L-citrulline ethyl ester + NH3
-
 ?
3.5.3.15 beta2-tubulin L-Arg + H2O
-
 Mus musculus beta2-tubulin L-citrulline + NH3
-
 ?
3.5.3.15 glial fibrillary acidic protein-L-Arg + H2O
-
 Mus musculus glial fibrillary acidic protein-L-citrulline + NH3
-
 ?
3.5.3.15 heat shock protein 8 L-Arg + H2O
-
 Mus musculus heat shock protein 8 L-citrulline + NH3
-
 ?
3.5.3.15 myelin basic protein-L-Arg + H2O
-
 Mus musculus myelin basic protein-L-citrulline + NH3
-
 ?
3.5.3.15 neuron-specific enolase 2 L-Arg + H2O
-
 Mus musculus neuron-specific enolase 2 L-citrulline + NH3
-
 ?
3.5.3.15 peptidylprolyl isomerase A L-Arg + H2O
-
 Mus musculus peptidylprolyl isomerase A L-citrulline + NH3
-
 ?
3.5.3.15 peroxiredoxin 1 L-Arg + H2O
-
 Mus musculus peroxiredoxin 1 L-citrulline + NH3
-
 ?
3.5.3.15 voltage-dependent anion channel 1 L-Arg + H2O
-
 Mus musculus voltage-dependent anion channel 1 L-citrulline + NH3
-
 ?
3.5.3.15 [cofilin 1]-L-Arg + H2O
-
 Mus musculus [cofilin 1]-L-citrulline + NH3
-
 ?
3.5.3.15 [mitochondrial malate dehydrogenase 2]-L-arginine + H2O
-
 Mus musculus [mitochondrial malate dehydrogenase 2]-L-citrulline + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.3.15 PAD2
-
 Mus musculus
3.5.3.15 peptidylarginine deiminase 2
-
 Mus musculus