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Literature summary extracted from

  • Lin, C.H.; Lin, C.W.; Khoo, K.H.
    Proteomic identification of specific glycosyltransferases functionally implicated for the biosynthesis of a targeted glyco-epitope (2008), Proteomics, 8, 475-483.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.65 Golgi membrane
-
 Homo sapiens 139
-
2.4.1.152 Golgi membrane
-
 Homo sapiens 139
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.65 Homo sapiens P21217 FucT3
-
2.4.1.65 Homo sapiens P51993 FucT6
-
2.4.1.152 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.65 native enzyme by preparation of microsome and Golgi membrane fractions, ultracentrifugation, and affinity chromatography Homo sapiens
2.4.1.152 native enzyme by preparation of microsome and Golgi membrane fractions, ultracentrifugation, and affinity chrotography Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.65 Colo-205 cell
-
 Homo sapiens
-
2.4.1.152 Colo-205 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.65 additional information FucT3 and FucT5 possess alpha1,4FucT activity to fucosylate type 1 chains, but FucT3, as well as FucT6, account also for alpha3-fucosylation of type 2 chain in Colo205. FucT3 alone is responsible for synthesizing Lea and (sialyl) Lewis a, (sialyl)Galb1-(Fucalpha1-4)3GlcNAcbeta-(s)Lea in Colo205 Homo sapiens ?
-
 ?
2.4.1.65 additional information FucT3 and FucT5 possess alpha1,4FucT activity to fucosylate type 1 chains, but FucT3, as well as FucT6, account also for alpha3-fucosylation of type 2 chain in Colo205. FucT3 alone is responsible for synthesizing Lea and (sialyl) Lewis a, (sialyl)Galbeta1-(Fucalpha1-4)3GlcNAcbeta-(s)Lea in Colo205 Homo sapiens ?
-
 ?
2.4.1.152 additional information FucT3 and FucT5 possess alpha1,4FucT activity to fucosylate type 1 chains, but FucT3, as well as FucT6, account also for alpha3-fucosylation of type 2 chain in Colo205. FucT3 alone is responsible for synthesizing Lea and (sialyl) Lewis a, (sialyl)Galb1-(Fucalpha1-4)3GlcNAcbeta-(s)Lea in Colo205 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.65 alpha3/4FucT
-
 Homo sapiens
2.4.1.152 alpha3/4FucT
-
 Homo sapiens