EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.10.1 | 5-fluorouracil | - |
Homo sapiens |
EC Number | Application | Comment | Organism |
---|---|---|---|
2.7.10.1 | medicine | a potential mechanism of action of Src kinase inhibitors on 5-fluorouracil chemosensitivity may be linked to the inhibition of 5-fluorouracil-induced EGFR-AKT activation | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.10.1 | 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine | PP2, combination of 5-fluorouracil-PP2 decreases the 5-fluorouracil-induced activation of EGFR-AKT pathway | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.10.1 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.10.1 | AsPC-1 cell | - |
Homo sapiens | - |
2.7.10.1 | L3.6pl cell | - |
Homo sapiens | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.10.1 | Egfr | - |
Homo sapiens |
2.7.10.1 | epidermal growth factor receptor | - |
Homo sapiens |