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Literature summary extracted from

  • Riballo, E.; Woodbine, L.; Stiff, T.; Walker, S.A.; Goodarzi, A.A.; Jeggo, P.A.
    XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation (2008), Nucleic Acids Res., 37, 482-492.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.5.1.1 XLF-Cernunnos a component of the DNA ligase IV-XRCC4 complex, which functions during DNA non-homologous end joining and stimulates ligase IV re-adenylation following ligation Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.5.1.1 expressed in Escherichia coli Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
6.5.1.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.5.1.1
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.5.1.1 2BN cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.5.1.1 ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.5.1.1 DNA ligase IV
-
 Homo sapiens
6.5.1.1 DNA ligase IV-XRCC4 complex
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
6.5.1.1 ATP
-
 Homo sapiens