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Literature summary extracted from

  • Jajoo, S.; Mukherjea, D.; Brewer, G.J.; Ramkumar, V.
    Pertussis toxin B-oligomer suppresses human immunodeficiency virus-1 Tat-induced neuronal apoptosis through feedback inhibition of phospholipase C-beta by protein kinase C (2008), Neuroscience, 151, 525-532.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.13 phorbol 12,13-dibutyrate
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.13 additional information Rattus norvegicus pertussis toxin-B suppresses HIV-1 Tat-mediated apoptosis by reducing its activation of phospholipase C-beta through a PKC activation pathway ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.13 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.13 cerebral cortical neuron
-
 Rattus norvegicus
-
2.7.11.13 PC-12 cell
-
 Rattus norvegicus
-
2.7.11.13 pheochromocytoma cell
-
 Rattus norvegicus
-
2.7.11.13 primary culture
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.13 additional information pertussis toxin-B suppresses HIV-1 Tat-mediated apoptosis by reducing its activation of phospholipase C-beta through a PKC activation pathway Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.13 PKC
-
 Rattus norvegicus