BRENDA - Enzyme Database

Involvement of lysophosphatidic acid, sphingosine 1-phosphate and ceramide 1-phosphate in the metabolization of phosphatidic acid by lipid phosphate phosphatases in bovine rod outer segments

Pasquare, S.J.; Salvador, G.A.; Giusto, N.M.; Neurochem. Res. 33, 1205-1215 (2008)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.3.4
additional information
light regulation of the lipid phosphate phosphatases, overview
Bos taurus
3.1.3.4
sphingosine 1-phosphate
activates overall cell lipid phosphate phosphatase activities by about 13%
Bos taurus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
additional information
light regulation of the lipid phosphate phosphatases, overview
Bos taurus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
membrane
-
Bos taurus
16020
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.3.4
a 3-sn-phosphatidate + H2O
Bos taurus
dephosphorylation of these lipids terminates their signaling actions and generates products with additional biological activities or metabolic fates, overview
a 1,2-diacyl-sn-glycerol + phosphate
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.3.4
Bos taurus
-
-
-
Posttranslational Modification
EC Number
Posttranslational Modification
Commentary
Organism
3.1.3.4
phosphoprotein
-
Bos taurus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.4
retina
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
1,2-diacyl-sn-glycerol 3-phosphate + H2O
-
694357
Bos taurus
1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
3.1.3.4
a 3-sn-phosphatidate + H2O
dephosphorylation of these lipids terminates their signaling actions and generates products with additional biological activities or metabolic fates, overview
694357
Bos taurus
a 1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
3.1.3.4
lysophosphatidic acid + H2O
-
694357
Bos taurus
? + phosphate
-
-
-
?
3.1.3.4
additional information
competition between phosphatidic acid, lysophosphatidic acid by the active site of LPPs is modulated by rod outer segment illumination state and by rod outer segment protein association/dissociation, overview
694357
Bos taurus
?
-
-
-
-
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
3.1.3.4
37
-
assay at
Bos taurus
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.1.3.4
6.5
-
assay at
Bos taurus
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.3.4
additional information
light regulation of the lipid phosphate phosphatases, overview
Bos taurus
3.1.3.4
sphingosine 1-phosphate
activates overall cell lipid phosphate phosphatase activities by about 13%
Bos taurus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.4
additional information
light regulation of the lipid phosphate phosphatases, overview
Bos taurus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.3.4
membrane
-
Bos taurus
16020
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.3.4
a 3-sn-phosphatidate + H2O
Bos taurus
dephosphorylation of these lipids terminates their signaling actions and generates products with additional biological activities or metabolic fates, overview
a 1,2-diacyl-sn-glycerol + phosphate
-
-
?
Posttranslational Modification (protein specific)
EC Number
Posttranslational Modification
Commentary
Organism
3.1.3.4
phosphoprotein
-
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.4
retina
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.4
1,2-diacyl-sn-glycerol 3-phosphate + H2O
-
694357
Bos taurus
1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
3.1.3.4
a 3-sn-phosphatidate + H2O
dephosphorylation of these lipids terminates their signaling actions and generates products with additional biological activities or metabolic fates, overview
694357
Bos taurus
a 1,2-diacyl-sn-glycerol + phosphate
-
-
-
?
3.1.3.4
lysophosphatidic acid + H2O
-
694357
Bos taurus
? + phosphate
-
-
-
?
3.1.3.4
additional information
competition between phosphatidic acid, lysophosphatidic acid by the active site of LPPs is modulated by rod outer segment illumination state and by rod outer segment protein association/dissociation, overview
694357
Bos taurus
?
-
-
-
-
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
3.1.3.4
37
-
assay at
Bos taurus
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.1.3.4
6.5
-
assay at
Bos taurus