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Literature summary extracted from

  • Mellman, D.L.; Gonzales, M.L.; Song, C.; Barlow, C.A.; Wang, P.; Kendziorski, C.; Anderson, R.A.
    A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs (2008), Nature, 451, 1013-1017.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.7.19 additional information other phosphoinositides besides phosphatidylinositol 4,5-bisphosphate do not affect Star-PAP activity, and no phosphoinositide has an effect on PAPalpha activity Saccharomyces cerevisiae
2.7.7.19 phosphatidylinositol 4,5-bisphosphate in the presence of 50 mM phosphatidylinositol 4,5-bisphosphate Star-PAP activity is markedly stimulated Saccharomyces cerevisiae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.19 expressed in HEK-293 cells Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.19 Cordycepin triphosphate 5.0 mM Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.19 nucleus
-
 Saccharomyces cerevisiae 5634
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.19 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.19
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.19 ATP + RNA
-
 Saccharomyces cerevisiae diphosphate + RNA(A)n
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.19 nuclear speckle targeted PIPKIalpha regulated-poly(A) polymerase
-
 Saccharomyces cerevisiae
2.7.7.19 PAPalpha
-
 Saccharomyces cerevisiae
2.7.7.19 poly(A) polymerase
-
 Saccharomyces cerevisiae
2.7.7.19 Star-PAP
-
 Saccharomyces cerevisiae