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Literature summary extracted from

  • Cravatt, B.F.; Giang, D.K.; Mayfield, S.P.; Boger, D.L.; Lerner, R.A.; Gilula, N.B.
    Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides (1996), Nature, 384, 83-87.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.1.99 expression in COS-7 cells Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.1.99 plasma membrane
-
 Rattus norvegicus 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.99 anandamide + H2O Rattus norvegicus
-
 ethanolamine + arachidonic acid
-
 ?
3.5.1.99 oleamide + H2O Rattus norvegicus
-
 oleic acid + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.99 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.99 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.99 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.99 anandamide + H2O
-
 Rattus norvegicus ethanolamine + arachidonic acid
-
 ?
3.5.1.99 myristic amide + H2O 24.3% of the activity with oleamide Rattus norvegicus myristic acid + NH3
-
 ?
3.5.1.99 oleamide + H2O
-
 Rattus norvegicus oleic acid + NH3
-
 ?
3.5.1.99 palmitic amide + H2O 9.9% of the activity with oleamide Rattus norvegicus palmitic acid + NH3
-
 ?
3.5.1.99 stearic amide + H2O 5.8% of the activity with oleamide Rattus norvegicus stearic acid + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.99 FAAH
-
 Rattus norvegicus
3.5.1.99 fatty-acid amide hydrolase
-
 Rattus norvegicus
3.5.1.99 oleamide hydrolase
-
 Rattus norvegicus