Literature summary extracted from

Jeon, J.; Goh, J.; Yoo, S.; Chi, M.H.; Choi, J.; Rho, H.S.; Park, J.; Han, S.S.; Kim, B.R.; Park, S.Y.; Kim, S.; Lee, Y.H.
A putative MAP kinase kinase kinase, MCK1, is required for cell wall integrity and pathogenicity of the rice blast fungus, Magnaporthe oryzae (2008), Mol. Plant Microbe Interact., 21, 525-534.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.11.25	additional information	Pyricularia oryzae	involved in maintaining cell wall integrity, remodeling of the cell wall in response to host environments is essential for fungal pathogenesis	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.11.25	Pyricularia oryzae	-	disruption of MCK1 resulted in the fungus undergoing autolysis and showing hypersensitivity to cell-wall-degrading enzyme, mutant strain produces significantly reduced numbers of conidia and developed appressoria in a slightly retarded manner compared with the wild type, mutant is unable to penetrate into plant tissues	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.11.25	additional information	involved in maintaining cell wall integrity, remodeling of the cell wall in response to host environments is essential for fungal pathogenesis	Pyricularia oryzae	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.11.25	MAPKKK	-	Pyricularia oryzae
2.7.11.25	MCK1	-	Pyricularia oryzae

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Release 2023.1 (January 2023)