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Literature summary extracted from

  • Parsa, K.V.; Butchar, J.P.; Rajaram, M.V.; Cremer, T.J.; Tridandapani, S.
    The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk (2008), Mol. Immunol., 45, 3012-3021.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.10.2
-
 Mus musculus
2.7.10.2
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.10.2 piceatannol
-
 Homo sapiens
2.7.10.2 piceatannol
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.2 ATP + [protein]-L-tyrosine Mus musculus
-
 ADP + [protein]-L-tyrosine phosphate
-
 ?
2.7.10.2 ATP + [protein]-L-tyrosine Homo sapiens
-
 ADP + [protein]-L-tyrosine phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.2 Homo sapiens P43405
-
-
2.7.10.2 Mus musculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.10.2 phosphoprotein Syk is phosphorylated in Francisella-infected cells Mus musculus
2.7.10.2 phosphoprotein Syk is phosphorylated in Francisella-infected cells Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.2 RAW-264.7 cell
-
 Mus musculus
-
2.7.10.2 THP-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.2 ATP + [protein]-L-tyrosine
-
 Mus musculus ADP + [protein]-L-tyrosine phosphate
-
 ?
2.7.10.2 ATP + [protein]-L-tyrosine
-
 Homo sapiens ADP + [protein]-L-tyrosine phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.2 Syk
-
 Mus musculus
2.7.10.2 Syk
-
 Homo sapiens