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Literature summary extracted from

  • Klusonova, P.; Kucka, M.; Ergang, P.; Miksik, I.; Bryndova, J.; Pacha, J.
    Cloning of chicken 11beta-hydroxysteroid dehydrogenase type 1 and its tissue distribution (2008), J. Steroid Biochem. Mol. Biol., 111, 217-224.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.146
-
 Gallus gallus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.146 Gallus gallus
-
-
-
1.1.1.146 Gallus gallus
-
 type 1 enzyme
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.1.1.146 glycoprotein sequence contains one N-linked glycosylation site Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.146 brain weak expression Gallus gallus
-
1.1.1.146 brain low level of expression, low acitivity Gallus gallus
-
1.1.1.146 gonad weak expression Gallus gallus
-
1.1.1.146 gonad low level of expression Gallus gallus
-
1.1.1.146 heart weak expression Gallus gallus
-
1.1.1.146 heart low level of expression, low activity Gallus gallus
-
1.1.1.146 intestine high expression Gallus gallus
-
1.1.1.146 intestine high level of expression and activity Gallus gallus
-
1.1.1.146 kidney high expression Gallus gallus
-
1.1.1.146 kidney high level of expression and activity Gallus gallus
-
1.1.1.146 liver high expression Gallus gallus
-
1.1.1.146 liver high level of expression and activity Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.146 corticosterone + NADP+
-
 Gallus gallus 11-dehydrocorticosterone + NADPH
-
 r
1.1.1.146 cortisol + NADP+
-
 Gallus gallus cortisone + NADPH
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.1.1.146 11beta-hydroxysteroid dehydrogenase type 1
-
 Gallus gallus
1.1.1.146 11HSD1
-
 Gallus gallus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.146 NADP+
-
 Gallus gallus