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Literature summary extracted from

  • Zhao, J.; Wu, H.W.; Chen, Y.J.; Tian, H.P.; Li, L.X.; Han, X.; Guo, J.
    Protein phosphatase 2A-negative regulation of the protective signaling pathway of Ca2+/CaM-dependent ERK activation in cerebral ischemia (2008), J. Neurosci. Res., 86, 2733-2745.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.16 ceramide ceramide induces increase of PP2A activity Rattus norvegicus

Application

EC Number Application Comment Organism
3.1.3.16 medicine PP2A inhibition may offer a new therapeutic approach to the treatment of diseases caused by cerebral ischemia Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.16 cantharidin
-
 Rattus norvegicus
3.1.3.16 okadaic acid
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.16 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.16 hippocampus
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.16 phosphorylated extracellular-signal-regulated kinase + H2O PP2A is involved in the inactivation, but not the activation, of extracellular-signal-regulated kinase Rattus norvegicus extracellular-signal-regulated kinase + phosphate
-
 ?
3.1.3.16 phosphorylated Raf + H2O Raf is dephosphorylated at Ser259 Rattus norvegicus Raf + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.16 PP2A
-
 Rattus norvegicus
3.1.3.16 protein phosphatase 2A
-
 Rattus norvegicus