EC Number | Crystallization (Comment) | Organism |
---|---|---|
4.2.1.141 | crystal structures of complexes of the enzyme with magnesium or calcium ions and either a substrate analog 2-oxobutyrate, or the aldehyde enzyme product 2,5-dioxopentanoate, 2.1 A resolution | Saccharolobus solfataricus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.141 | additional information | crystal structures of complexes of the enzyme with magnesium or calcium ions and either a substrate analog 2-oxobutyrate, or the aldehyde enzyme product 2,5-dioxopentanoate reveal the divalent metal ion in the active site is coordinated octahedrally by three conserved carboxylate residues, a water molecule, and both the carboxylate and the oxo groups of the substrate molecule | Saccharolobus solfataricus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate | Saccharolobus solfataricus | key enzyme in degradation of D-arabinose | 2,5-dioxopentanoate + H2O | - |
? | |
4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate | Saccharolobus solfataricus P2 | key enzyme in degradation of D-arabinose | 2,5-dioxopentanoate + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.141 | Saccharolobus solfataricus | Q97UA0 | - |
- |
4.2.1.141 | Saccharolobus solfataricus P2 | Q97UA0 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate | - |
Saccharolobus solfataricus | 2,5-dioxopentanoate + H2O | - |
? | |
4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate | key enzyme in degradation of D-arabinose | Saccharolobus solfataricus | 2,5-dioxopentanoate + H2O | - |
? | |
4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate | - |
Saccharolobus solfataricus P2 | 2,5-dioxopentanoate + H2O | - |
? | |
4.2.1.141 | 2-dehydro-3-deoxy-D-arabinonate | key enzyme in degradation of D-arabinose | Saccharolobus solfataricus P2 | 2,5-dioxopentanoate + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.141 | D-KDA dehydratase | - |
Saccharolobus solfataricus |
4.2.1.141 | KdaD | - |
Saccharolobus solfataricus |
4.2.1.141 | Sso3118 | - |
Saccharolobus solfataricus |