EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.6.1.2 | cone-specific calcium sensor guanylate cyclase activating protein 4 | encoded by gene zGCAP4 from zebrafish, cloning and expression in Escherichia coli, zGCAP4 is a strong activator of membrane-bound guanylate cyclases from bovine retina, mainly present as a monomer and showing half-maximal activation at 520-570 nM free Ca2+ concentration | Bos taurus | |
4.6.1.2 | cone-specific calcium sensor guanylate cyclase activating protein 4 | encoded by gene zGCAP4 from zebrafish, cloning and expression in Escherichia coli, zGCAP4 is a strong activator of membrane-bound guanylate cyclases from zebrafish retina, mainly present as a monomer and showing half-maximal activation at 520-570 nM free Ca2+ concentration | Danio rerio |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
4.6.1.2 | membrane | - |
Bos taurus | 16020 | - |
4.6.1.2 | membrane | - |
Danio rerio | 16020 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.6.1.2 | Ca2+ | activates, is required for activation of the retinal enzyme by cone-specific calcium sensor guanylate cyclase activating protein 4 | Bos taurus | |
4.6.1.2 | Ca2+ | activates, is required for activation of the retinal enzyme by cone-specific calcium sensor guanylate cyclase activating protein 4 | Danio rerio |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.2 | GTP | Bos taurus | - |
3',5'-cyclic GMP + diphosphate | - |
? | |
4.6.1.2 | GTP | Danio rerio | - |
3',5'-cyclic GMP + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.6.1.2 | Bos taurus | - |
- |
- |
4.6.1.2 | Danio rerio | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.6.1.2 | retina | - |
Bos taurus | - |
4.6.1.2 | retina | - |
Danio rerio | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.6.1.2 | GTP | - |
Bos taurus | 3',5'-cyclic GMP + diphosphate | - |
? | |
4.6.1.2 | GTP | - |
Danio rerio | 3',5'-cyclic GMP + diphosphate | - |
? |