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Literature summary extracted from

  • Shimizu, A.; Mammoto, A.; Italiano, J.E.; Pravda, E.; Dudley, A.C.; Ingber, D.E.; Klagsbrun, M.
    ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells (2008), J. Biol. Chem., 283, 27230-27238.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.7.10.2 medicine Abl1 and Abl2 have a role in axonogenesis and cancer Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.10.2 into the pcDNA3.1 TOPO vector Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.10.2 siRNA
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.10.2 membrane
-
 Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.2 ATP + [protein]-L-tyrosine Homo sapiens
-
 ADP + [protein]-L-tyrosine phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.2 endothelial cell
-
 Homo sapiens
-
2.7.10.2 U-87MG cell
-
 Homo sapiens
-
2.7.10.2 umbilical vein endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.2 ATP + [protein]-L-tyrosine
-
 Homo sapiens ADP + [protein]-L-tyrosine phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.2 Abelson tyrosine kinase
-
 Homo sapiens
2.7.10.2 ABL2
-
 Homo sapiens
2.7.10.2 ABL2/ARG tyrosine kinase
-
 Homo sapiens
2.7.10.2 ARG
-
 Homo sapiens