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Literature summary extracted from
- Topoisomerase I requirement for death receptor-induced apoptotic nuclear fission (2008), J. Biol. Chem., 283, 23200-23208.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.2.1 | antimycin A | - |
Homo sapiens |  |
| 5.6.2.1 | BH3I-2' | - |
Homo sapiens | |
| 5.6.2.1 | tumor necrosis factor-related apoptosis-inducing ligand | TRAIL | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.2.1 | camptothecin | - |
Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.2.1 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.2.1 | HCT-116 cell | colon carcinoma cell lines | Homo sapiens | - |
| 5.6.2.1 | JURKAT cell | human leukemia cell line | Homo sapiens | - |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.6.2.1 | Top1 | - |
Homo sapiens |
| 5.6.2.1 | Topoisomerase I | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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