EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.11.9 | gene COL4A3BP, located on chromosome 5, the gene product is alternatively spliced producing two protein isozymes: GPBP and GPBPDELTA26, DNA and amino acid sequence determination and analysis, expression of wild-type and mutant isozyme GPBP in HEK-293 cells | Danio rerio |
2.7.11.9 | gene COL4A3BP, located on chromosome 5, the gene product is alternatively spliced producing two protein isozymes: GPBP and GPBPDELTA26, DNA and amino acid sequence determination and analysis, expression of wild-type and mutant isozyme GPBPDELTA26 in HEK-293 cells | Danio rerio |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.7.11.9 | additional information | construction of antisense oligonucleotide-mediated loss-of-function and synthetic mRNA-based gain-of-function mutants. The loss-of-function phenotype is linked to cell death, evident primarily in the muscle of the somites, extensive loss of myelinated tracks, and brain edema, phenotype, overview | Danio rerio |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.9 | ATP + [Goodpasture antigen-binding protein] | Danio rerio | the Goodpasture antigen-binding protein is an atypical protein kinase that phosphorylates the Goodpasture auto-antigen, the alpha3 chain of collagen IV | ADP + [Goodpasture antigen-binding phosphoprotein] | - |
? | |
2.7.11.9 | additional information | Danio rerio | disruption of the nonvesicular ceramide transport is detrimental to normal embryonic development of somites and brain because of increased apoptosis mediated by the CERT function of GBPB, but not GBPBDELT26, overview | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.9 | Danio rerio | Q5M7Y0 | GPBP; gene COL4A3BP | - |
2.7.11.9 | Danio rerio | Q5M7Y0 | GPBPDELTA26; gene COL4A3BP | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.9 | additional information | isozymes GPBP and GPBPDELTA26 are differentially expressed during development, isozymes function during embryogenesis, GPBP is an important factor for normal skeletal muscle and brain development, overview | Danio rerio | - |
2.7.11.9 | additional information | isozymes GPBP and GPBPDELTA26 are differentially expressed during development, isozymes function during embryogenesis, overview | Danio rerio | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.9 | ATP + [Goodpasture antigen-binding protein] | the Goodpasture antigen-binding protein is an atypical protein kinase that phosphorylates the Goodpasture auto-antigen, the alpha3 chain of collagen IV | Danio rerio | ADP + [Goodpasture antigen-binding phosphoprotein] | - |
? | |
2.7.11.9 | additional information | disruption of the nonvesicular ceramide transport is detrimental to normal embryonic development of somites and brain because of increased apoptosis mediated by the CERT function of GBPB, but not GBPBDELT26, overview | Danio rerio | ? | - |
? | |
2.7.11.9 | additional information | isozyme GPBP also function as ceramide transfer proteins, CERT | Danio rerio | ? | - |
? | |
2.7.11.9 | additional information | isozyme GPBPDELTA26 also functions as ceramide transfer protein, CERT | Danio rerio | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.9 | GPBP | - |
Danio rerio |
2.7.11.9 | GPBPDELTA26 | - |
Danio rerio |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.9 | ATP | - |
Danio rerio |