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Literature summary extracted from

  • Banchio, C.; Lingrell, S.; Vance, D.E.
    Sp-1 binds promoter elements that are regulated by retinoblastoma and regulate CTP:phosphocholine cytidylyltransferase-alpha transcription (2007), J. Biol. Chem., 282, 14827-14835.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.7.15 retinoblastoma protein regulates CTalpha expression by different mechanisms depending on the phase of the cell cycle, the regulation of CTalpha expression requires both the Sp1 and the retinoblastoma control elements Mus musculus
2.7.7.15 Sp1 Sp1 stimulates CTalpha transcription, and Sp1-mediated transcription is stimulated by the retinoblastoma protein Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.15 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.15 C3H10T1/2 cell
-
 Mus musculus
-
2.7.7.15 MEF cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.15 CTP + choline phosphate
-
 Mus musculus diphosphate + CDP-choline
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.15 CTalpha
-
 Mus musculus
2.7.7.15 CTP:phosphocholine cytidylyltransferase-alpha
-
 Mus musculus